Study the Suppression of Preterm Labor Using Human Chorionic Gonadotropin Hormone Compared with Magnesium Sulphate

Preterm labor is known as delivery prior to 37 completed weeks of gestation. Because 10% total labors are preterm and 70% neonatal mortality caused by this problem, a significant problem in obstetrics, pediatrics & midwifery. This study aims at comparing the efficacy well adverse effects profile (human chorionic gonadotropin hormone magnesium sulphate) suppression labor. was designed prospective comparative randomized clinical trial done from 4th April 1st September 2020. The population included pregnant women with labor, who were admitted Salah Al Din General Hospital, Tikrit city. Sixty two cases consented (Informed written consent obtained all patients) randomly allocated 2 different intervention groups, named A B. Group B consisted 30 32 women, respectively. All labour room baseline investigations done. A: For patients group received an intravenously loading dose 4 g (1 g/min) Magnesium sulphate. continual infusion per 1 hr then administrated. continued until 12 h uterine quiescence B: (32 women), intramuscular injection Human Chorionic Gonadotropin administered initial 5000 IU. Half hourly assessment contractions, maternal vital signs, fetal heart rate monitoring under hospital 24 end drug infusion. Also, both groups Betamethasone, mg every for doses. Patients control pregnancy. It foun that Delay Labour ≥21 day higher among (68.8%) than MgSO4 (60%), within <2 days HCG (9.4%) (6.7%). mean duration hours time start treatment sulphate contraction (2.9±0.08) lower (3.11±0.13). commonest side effect thirst (50%), hyperthermia (46.67), head ache (30%), dizziness while there no except single case complained (3.13%), concluded better stopping faster onset action but had mothers more Gonadotropin.